发明申请
- 专利标题： ANIMAL MODEL AND A METHOD FOR PRODUCING AN ANIMAL MODEL
- 专利标题（中）： 动物模型和一种生产动物模型的方法
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申请号： US12298974申请日： 2007-04-30
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公开(公告)号： US20090304595A1公开(公告)日： 2009-12-10
- 发明人: Lone Bruhn Madsen , Christian Bendixen , Knud Larsen , Connie Jacobsen Juhl , Bo Thomsen
- 申请人： Lone Bruhn Madsen , Christian Bendixen , Knud Larsen , Connie Jacobsen Juhl , Bo Thomsen
- 申请人地址： DK Arhus C
- 专利权人： Aarhus Universitet
- 当前专利权人： Aarhus Universitet
- 当前专利权人地址： DK Arhus C
- 优先权： DKPA200600616 20060501; DKPA20700429 20070320
- 国际申请： PCT/DK2007/000204 WO 20070430
- 主分类号： A01K67/02
- IPC分类号： A01K67/02 ; A01K67/00 ; A61K49/00 ; C12N5/06 ; C12N15/85 ; A01K67/027 ; A61D19/02
摘要：
The present invention discloses a non-human animal model for a hereditary autosomal dominant disease. The non-human animal model expresses at least one phenotype associated with the disease and is obtained by a genetic determinant. The invention also relates to sperm cells and embryos comprising the genetic determinant for an autosomal dominant disease. Furthermore, methods for producing the non-human animal model, sperm cell, and embryos are disclosed.