- 专利标题： In vitro engineered, regenerated urinary tract tissue compositions and methods for producing same
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申请号： US12456377申请日： 2009-06-16
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公开(公告)号： US20090304645A1公开(公告)日： 2009-12-10
- 发明人: Bradley P. Kropp , Earl Y. Cheng , Yuan Yuan Zhang , Rick Cowan , Peter Moore
- 申请人： Bradley P. Kropp , Earl Y. Cheng , Yuan Yuan Zhang , Rick Cowan , Peter Moore
- 主分类号： A61K35/12
- IPC分类号： A61K35/12 ; A61P43/00
摘要：
A method for providing a urinary tract tissue graft composition includes providing a tissue culture frame and a segment of small intestinal submucosa and positioning the segment of small intestinal submucosa in the tissue culture frame such that the segment of small intestinal submucosa is suspended and held in a taut position by the tissue culture frame. Smooth muscle and urothelial cells are isolated from a tissue specimen of a subject and cultured, and then seeded upon the segment of small intestinal submucosa, thereby forming a urinary tract tissue graft. A tissue culture frame in which such a urinary tract tissue graft may be formed is also disclosed.
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