发明申请
- 专利标题： COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS
- 专利标题（中）： 化合物和组合物作为ITPKB抑制剂
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申请号： US12374481申请日： 2007-07-20
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公开(公告)号： US20090306039A1公开(公告)日： 2009-12-10
- 发明人: Shifeng Pan , Yi Liu , Yun Feng Xie , Dai Cheng , yongqin Wan , Dong Han , Yang Yang , Wenqi Gao , Jiqing Jiang , Badry Bursulaya , Philip Chamberlain , Donald Karanewsky , Xia Wang
- 申请人： Shifeng Pan , Yi Liu , Yun Feng Xie , Dai Cheng , yongqin Wan , Dong Han , Yang Yang , Wenqi Gao , Jiqing Jiang , Badry Bursulaya , Philip Chamberlain , Donald Karanewsky , Xia Wang
- 国际申请： PCT/US07/74048 WO 20070720
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D403/06 ; C07D401/14 ; C07D403/14 ; C07D413/14 ; A61K31/506 ; A61K31/551 ; A61K31/5377
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated B cell activities, particularly diseases or disorders that involve aberrant activation of inositol 1,4,5-trisphosphate 3-kinase B (ITPKb).
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