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公开(公告)号:US20090306039A1
公开(公告)日:2009-12-10
申请号:US12374481
申请日:2007-07-20
申请人: Shifeng Pan , Yi Liu , Yun Feng Xie , Dai Cheng , yongqin Wan , Dong Han , Yang Yang , Wenqi Gao , Jiqing Jiang , Badry Bursulaya , Philip Chamberlain , Donald Karanewsky , Xia Wang
发明人: Shifeng Pan , Yi Liu , Yun Feng Xie , Dai Cheng , yongqin Wan , Dong Han , Yang Yang , Wenqi Gao , Jiqing Jiang , Badry Bursulaya , Philip Chamberlain , Donald Karanewsky , Xia Wang
IPC分类号: A61K31/496 , C07D403/06 , C07D401/14 , C07D403/14 , C07D413/14 , A61K31/506 , A61K31/551 , A61K31/5377
CPC分类号: C07D401/12 , C07D231/12 , C07D401/14 , C07D413/14 , C07D487/08 , C07D491/04
摘要: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated B cell activities, particularly diseases or disorders that involve aberrant activation of inositol 1,4,5-trisphosphate 3-kinase B (ITPKb).
摘要翻译: 本发明提供了一类新颖的化合物,包含这些化合物的药物组合物和使用这些化合物治疗或预防与异常或失调的B细胞活性相关的疾病或病症的方法,特别是涉及肌醇1,4异常活化的疾病或病症, 5-三磷酸3-激酶B(ITPKb)。
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公开(公告)号:US08178526B2
公开(公告)日:2012-05-15
申请号:US12664651
申请日:2008-06-12
申请人: Badry Bursulaya , Dai Cheng , Jiqing Jiang , Donald S. Karanewsky , Yi Liu , Shifeng Pan , Yongqin Wan , Xia Wang , Yun Feng Xie , Yang Yang
发明人: Badry Bursulaya , Dai Cheng , Jiqing Jiang , Donald S. Karanewsky , Yi Liu , Shifeng Pan , Yongqin Wan , Xia Wang , Yun Feng Xie , Yang Yang
IPC分类号: C07D413/02 , C07D413/14 , A61K31/536 , A61K31/551
CPC分类号: C07D413/14 , C07D413/02
摘要: The invention provides a novel class of compounds of formula (I), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or dysregulated B cell activities, particularly diseases or disorders that involve aberrant activation of inositol 1,4,5-trisphosphate 3-kinase B (ITPKb).
摘要翻译: 本发明提供了一类新颖的式(I)化合物,包含这些化合物的药物组合物和使用这些化合物治疗或预防与异常或失调B细胞活性相关的疾病或病症的方法,特别是涉及异常活化的疾病或病症 肌醇1,4,5-三磷酸3-激酶B(ITPKb)。
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公开(公告)号:US20120202782A1
公开(公告)日:2012-08-09
申请号:US13445644
申请日:2012-04-12
申请人: Badry Bursulaya , Dai Cheng , Jiqing Jiang , Donald S. Karanewsky , Yi Liu , Shifeng Pan , Yongqin Wan , Xia Wang , Yun Feng Xie , Yang Yang
发明人: Badry Bursulaya , Dai Cheng , Jiqing Jiang , Donald S. Karanewsky , Yi Liu , Shifeng Pan , Yongqin Wan , Xia Wang , Yun Feng Xie , Yang Yang
IPC分类号: A61K31/536 , A61K31/551 , A61K31/496 , A61K31/4985 , C07D487/08 , A61K31/538 , C07D401/14 , A61K31/517 , A61P37/06 , A61P29/00 , A61P19/02 , A61P17/06 , A61P7/06 , A61P35/00 , C07D413/14
CPC分类号: C07D413/14 , C07D413/02
摘要: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or dysregulated B cell activities, particularly diseases or disorders that involve aberrant activation of inositol 1,4,5-trisphosphate 3-kinase B (ITPKb).
摘要翻译: 本发明提供了一类新颖的化合物,包含这些化合物的药物组合物和使用这些化合物治疗或预防与异常或失调的B细胞活性有关的疾病或病症的方法,特别是涉及肌醇1,4异常活化的疾病或病症, 5-三磷酸3-激酶B(ITPKb)。
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公开(公告)号:US20100184748A1
公开(公告)日:2010-07-22
申请号:US12664651
申请日:2008-06-12
申请人: Badry Bursulaya , Dai Cheng , Jiqing Jiang , Donald S. Karanewsky , Yi Liu , Shifeng Pan , Yongqin Wan , Xia Wang , Yun Feng Xie , Yang Yang
发明人: Badry Bursulaya , Dai Cheng , Jiqing Jiang , Donald S. Karanewsky , Yi Liu , Shifeng Pan , Yongqin Wan , Xia Wang , Yun Feng Xie , Yang Yang
IPC分类号: A61K31/536 , C07D413/14 , A61K31/551 , A61P35/00
CPC分类号: C07D413/14 , C07D413/02
摘要: The invention provides a novel class of compounds of formula (I), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or dysregulated B cell activities, particularly diseases or disorders that involve aberrant activation of inositol 1,4,5-trisphosphate 3-kinase B (ITPKb).
摘要翻译: 本发明提供了一类新颖的式(I)化合物,包含这些化合物的药物组合物和使用这些化合物治疗或预防与异常或失调的B细胞活性有关的疾病或病症的方法,特别是涉及异常活化的疾病或病症 肌醇1,4,5-三磷酸3-激酶B(ITPKb)。
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公开(公告)号:US20110263610A1
公开(公告)日:2011-10-27
申请号:US12935273
申请日:2009-03-30
申请人: Yongqin Wan , Shifeng Pan , Guobao Zhang , Xia Wang , Yun Feng Xie , Jiqing Jiang , Dean Phillips , Yang Yang
发明人: Yongqin Wan , Shifeng Pan , Guobao Zhang , Xia Wang , Yun Feng Xie , Jiqing Jiang , Dean Phillips , Yang Yang
IPC分类号: C07D487/04 , C07D405/14 , A61P19/02 , A61P17/06 , A61P37/00 , A61K31/496 , C07D401/14
CPC分类号: C07D401/14 , C07D407/14 , C07D409/14 , C07D471/04
摘要: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated B cell activities, particularly diseases or disorders that involve aberrant activation of inositol 1,4,5-trisphosphate 3-kinase B (ITPKb).
摘要翻译: 本发明提供了一类新颖的化合物,包含这些化合物的药物组合物和使用这些化合物治疗或预防与异常或失调的B细胞活性相关的疾病或病症的方法,特别是涉及肌醇1,4异常活化的疾病或病症, 5-三磷酸3-激酶B(ITPKb)。
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公开(公告)号:USD1025689S1
公开(公告)日:2024-05-07
申请号:US29884242
申请日:2023-02-09
申请人: Yang Yang
设计人: Yang Yang
摘要: FIG. 1 is a front, right and top perspective view of a bottle cap, showing my design.
FIG. 2 is a rear, left and bottom perspective view thereof.
FIG. 3 is a front elevation view thereof.
FIG. 4 is a rear elevation view thereof.
FIG. 5 is a left side elevation view thereof.
FIG. 6 is a right side elevation view thereof.
FIG. 7 is a top plan view thereof.
FIG. 8 is a bottom plan view thereof; and,
FIG. 9 is an enlarged view of detail 9 in FIG. 1.
The broken lines depict portions of the bottle cap that form no part of the claimed design.
The dot-dash broken lines in FIGS. 1 and 9 depict the boundaries of the enlargements that form no part of the claimed design.-
公开(公告)号:US20220298242A1
公开(公告)日:2022-09-22
申请号:US17636440
申请日:2020-07-23
摘要: The present invention provides an anti-CD3 single chain Fab molecule and an anti-CD20 single chain Fab molecule and their use in preparation of a bispecific antibody. The present invention also provides a bispecific antibody targeting CD3 and CD20 and its use in preparation of a medicament for treatment of a B-cell related disease.
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公开(公告)号:US11424860B2
公开(公告)日:2022-08-23
申请号:US16617475
申请日:2018-06-29
发明人: Jing Jiang , Yang Yang , Joseph Binamira Soriaga
摘要: Methods and apparatus are provided for selecting a code type. A type of code is selected from a set of code types to use as an inner code for a concatenated encoding scheme for encoding information bits of a channel, wherein the selection is based on one or more channel coding parameters including a false alarm detection objective for the channel. A codeword is generated by encoding the information bits using the type of codes selected as the inner code and an outer code. The generated codeword is transmitted.
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公开(公告)号:US10779283B2
公开(公告)日:2020-09-15
申请号:US15168991
申请日:2016-05-31
申请人: Yigang Cai , Yang Yang
发明人: Yigang Cai , Yang Yang
摘要: The present disclosure generally discloses a wireless resource sharing mechanism configured to support sharing of physical wireless resources of a wireless interface of a wireless access device. The wireless resource sharing mechanism is configured to support sharing of physical wireless resources of a wireless interface of a wireless access device in order to support Machine-Type Communications (MTCs). The wireless resource sharing mechanism is configured to support sharing of physical wireless resources, of a wireless interface of a wireless access device, between MTC traffic of MTC devices and non-MTC traffic of non-MTC devices (referred to herein as legacy traffic of legacy devices). The wireless resource sharing mechanism is configured to support sharing of physical wireless resources, of a wireless interface of a wireless access device, within a scheduling time interval of the wireless interface of the wireless access device.
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公开(公告)号:US09831424B2
公开(公告)日:2017-11-28
申请号:US14809770
申请日:2015-07-27
申请人: James M. Tour , Gunuk Wang , Yang Yang
发明人: James M. Tour , Gunuk Wang , Yang Yang
IPC分类号: H01L27/108 , H01L45/00 , H01L27/24
CPC分类号: H01L45/08 , H01L27/2472 , H01L45/1233 , H01L45/146 , H01L45/1633
摘要: A nanoporous (NP) memory may include a non-porous layer and a nanoporous layer sandwiched between the bottom and top electrodes. The memory may be free of diodes, selectors, and/or transistors that may be necessary in other memories to mitigate crosstalk. The nanoporous material of the nanoporous layer may be a metal oxide, metal chalcogenide, or a combination thereof. Further, the memory may lack any additional components. Further, the memory may be free from requiring an electroformation process to allow switching between ON/OFF states.
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