发明申请
- 专利标题： HETEROARYL 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS
- 专利标题（中）： 异戊二烯脱氢酶脱氢酶I型抑制剂
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申请号： US12509541申请日： 2009-07-27
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公开(公告)号： US20090306084A1公开(公告)日： 2009-12-10
- 发明人: James J. Li , Lawrence G. Hamann , Haixia Wang
- 申请人： James J. Li , Lawrence G. Hamann , Haixia Wang
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 主分类号： A61K31/503
- IPC分类号： A61K31/503 ; A61K31/4745 ; A61K31/4192 ; C07D471/02 ; C07D249/16
摘要：
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: W-L-Z (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein W, L and Z are defined herein.
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