发明申请
US20090311699A1 METHOD OF SURFACE PLASMON RESONANCE (SPR) TO DETECT GENOMIC ABERRATIONS IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA
审中-公开
表面等离子体共振(SPR)检测慢性淋巴细胞白血病患者基因型异常的方法
- 专利标题: METHOD OF SURFACE PLASMON RESONANCE (SPR) TO DETECT GENOMIC ABERRATIONS IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA
- 专利标题(中): 表面等离子体共振(SPR)检测慢性淋巴细胞白血病患者基因型异常的方法
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申请号: US12441708申请日: 2007-08-22
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公开(公告)号: US20090311699A1公开(公告)日: 2009-12-17
- 发明人: Zhong Chen , Ning Liu
- 申请人: Zhong Chen , Ning Liu
- 申请人地址: VG Road Town, Tortola
- 专利权人: CMED TECHNOLOGIES LTD.
- 当前专利权人: CMED TECHNOLOGIES LTD.
- 当前专利权人地址: VG Road Town, Tortola
- 国际申请: PCT/US07/76472 WO 20070822
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C12M1/34
摘要:
This invention discloses using SPR technology to detect CLL related genomic aberrations in peripheral blood samples. An efficient formula to make a mixed SAM that can greatly enhance the immobilization ability of the metal surface in SPR based techniques, which is good for the immobilization of CLL related DNA markers used for the detection of genomic aberrations for patients with chronic lymphocytic leukemia (CLL) is also disclosed.
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