发明申请
US20090311701A1 Organ-specific gene, method for identifying the same and use thereof
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器官特异性基因，鉴定其的方法及其用途
- 专利标题： Organ-specific gene, method for identifying the same and use thereof
- 专利标题（中）： 器官特异性基因，鉴定其的方法及其用途
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申请号： US12447446申请日： 2007-10-26
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公开(公告)号： US20090311701A1公开(公告)日： 2009-12-17
- 发明人: Saku Miyamoto , Kenji Takami , Akira Horinouchi
- 申请人： Saku Miyamoto , Kenji Takami , Akira Horinouchi
- 申请人地址： JP OSAKA-SHI OSAKA
- 专利权人： TAKEDA PHARMACEUTICAL COMPANY LIMITED
- 当前专利权人： TAKEDA PHARMACEUTICAL COMPANY LIMITED
- 当前专利权人地址： JP OSAKA-SHI OSAKA
- 优先权： JP2006-293324 20061027
- 国际申请： PCT/JP2007/070944 WO 20071026
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C07H21/04
摘要：
The present invention provides a method of extracting an organ- or tissue-specific highly expressed gene, including:(1) a step for measuring expression level of a specified gene group for each organ or tissue in 2 or more individuals, (2) a step for acquiring (a) a minimum value of expression levels in a particular organ or tissue in all individuals, and (b) a maximum value of expression levels in other organs and tissues in all individuals, for each gene, and (3) a step for extracting the gene as a gene highly expressed specifically in the particular organ or tissue if the above-described (a)/(b) ratio is larger than 1. By the present invention, truly organ- or tissue-specific genes are extracted.
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