发明申请
US20090324507A1 RNAi-Mediated Inhibition of Spleen Tyrosine Kinase-Related Inflammatory Conditions
有权
RNAi介导的脾脏酪氨酸激酶相关炎症病症的抑制
- 专利标题： RNAi-Mediated Inhibition of Spleen Tyrosine Kinase-Related Inflammatory Conditions
- 专利标题（中）： RNAi介导的脾脏酪氨酸激酶相关炎症病症的抑制
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申请号： US12296621申请日： 2007-04-13
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公开(公告)号： US20090324507A1公开(公告)日： 2009-12-31
- 发明人: John M. Yanni , Jon E. Chatterton , Daniel A. Gamache , Steven T. Miller
- 申请人： John M. Yanni , Jon E. Chatterton , Daniel A. Gamache , Steven T. Miller
- 申请人地址： US TX Fort Worth
- 专利权人： ALCON RESEARCH, LTD.
- 当前专利权人： ALCON RESEARCH, LTD.
- 当前专利权人地址： US TX Fort Worth
- 优先权： USPCT/US2007/066619 20070413
- 国际申请： PCT/US07/66619 WO 20070413
- 主分类号： A61K9/12
- IPC分类号： A61K9/12 ; A61K31/7105 ; A61K48/00
摘要：
RNA interference is provided for inhibition of spleen tyrosine kinase (Syk) mRNA expression, in particular, for treating patients having a Syk-related inflammatory condition or at risk of developing a Syk-related inflammatory condition such as allergic conjunctivitis, ocular inflammation, dermatitis, rhinitis, asthma, allergy, or mast-cell disease.
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