发明申请
US20090326359A1 METHOD OF IN VIVO DETECTION AND/OR DIAGNOSIS OF CANCER USING FLUORESCENCE BASED DNA IMAGE CYTOMETRY
审中-公开
使用基于荧光的DNA图像细胞计数检测和/或诊断癌症的方法
- 专利标题： METHOD OF IN VIVO DETECTION AND/OR DIAGNOSIS OF CANCER USING FLUORESCENCE BASED DNA IMAGE CYTOMETRY
- 专利标题（中）： 使用基于荧光的DNA图像细胞计数检测和/或诊断癌症的方法
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申请号： US12375776申请日： 2007-07-11
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公开(公告)号： US20090326359A1公开(公告)日： 2009-12-31
- 发明人: Bernardus Hendrikus Wilhelmus Hendriks , Ruth Wihelmine Ireen De Boer , Gerhard Spekowius , Stein Kuipeer , Nijs Cornelis Van Der Vaart
- 申请人： Bernardus Hendrikus Wilhelmus Hendriks , Ruth Wihelmine Ireen De Boer , Gerhard Spekowius , Stein Kuipeer , Nijs Cornelis Van Der Vaart
- 申请人地址： NL EINDHOVEN
- 专利权人： KONINKLIJKE PHILIPS ELECTRONICS N.V.
- 当前专利权人： KONINKLIJKE PHILIPS ELECTRONICS N.V.
- 当前专利权人地址： NL EINDHOVEN
- 优先权： EP06118437.0 20060804
- 国际申请： PCT/IB07/52764 WO 20070711
- 主分类号： A61B6/00
- IPC分类号： A61B6/00
摘要：
The invention relates to a method of determining in vivo in a human or animal subject the amount of nuclear DNA by first localizing cell nuclei of living tissue and subsequently measuring the nuclear UV absorbance using confocal scanning microscopy. The invention relates also to a method for detecting cancerous cells in vivo in a human or animal subject by first identifying the localization of cell nuclei in living tissue and subsequently determining the nuclear UV absorbance by laser scanning confocal microscopy. Furthermore, the invention relates to a method of diagnosing cancer in a human or animal subject in vivo relying on a combination of identifying the localization of cell nuclei in living tissue and measuring nuclear UV absorbance by laser scanning confocal microscopy.
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