A method and a device for operating an internal combustion engine make it possible to shift the combustion limit. In this context, a predefined output variable of the internal combustion engine such as the torque, for example, is realized in at least one operating state of the internal combustion engine by at least a retardation of an ignition angle. It is checked whether, due to the retardation of the ignition angle, a variable like, for example, a misfiring, characteristic for the combustibility of the air/fuel mixture in a combustion chamber of the internal combustion engine, exceeds a predefined limiting value in terms of a deterioration of the combustibility, and in this case, at least one actuator of the internal combustion engine, different from an actuator for setting the ignition angle, such as the exhaust-gas recirculation valve or EGR valve, for instance, is controlled along the lines of improving the combustibility of the air/fuel mixture.