发明申请
US20100003250A1 (2-ARYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)MORPHOLINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES
审中-公开
（2-ARYL-7H-吡咯并[2,3-D]嘧啶-4-基）吗啉化合物，它们作为MTOR激酶和PI3激酶抑制剂使用，以及它们的合成
![(2-ARYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)MORPHOLINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES](/docs/US/2010-01-07/US20100003250A1/abs.jpg.600x600.jpg)
- 专利标题： (2-ARYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)MORPHOLINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES
- 专利标题（中）： （2-ARYL-7H-吡咯并[2,3-D]嘧啶-4-基）吗啉化合物，它们作为MTOR激酶和PI3激酶抑制剂使用，以及它们的合成
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申请号： US12496675申请日： 2009-07-02
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公开(公告)号： US20100003250A1公开(公告)日： 2010-01-07
- 发明人: Zecheng Chen , Aranapakam Mudumbai Venkatesan , Arie Zask , Jeroen Cunera Verheijen , Semiramis Ayral-Kaloustian , Tarek Suhayl Mansour , Kevin Joseph Curran
- 申请人： Zecheng Chen , Aranapakam Mudumbai Venkatesan , Arie Zask , Jeroen Cunera Verheijen , Semiramis Ayral-Kaloustian , Tarek Suhayl Mansour , Kevin Joseph Curran
- 申请人地址： US NJ Madison
- 专利权人： Wyeth
- 当前专利权人： Wyeth
- 当前专利权人地址： US NJ Madison
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D487/04 ; A61K39/395 ; A61P35/00
![(2-ARYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)MORPHOLINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES](/abs-image/US/2010/01/07/US20100003250A1/abs.jpg.150x150.jpg)
摘要：
The invention relates to 2-aryl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)morpholine compounds of the Formula I: or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.
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