发明申请
US20100003681A1 GENE POLYMORPHISM USEFUL FOR ASSISTANCE/THERAPY FOR SMOKING CESSATION
审中-公开
基因多态性有助于帮助/治疗吸烟
- 专利标题: GENE POLYMORPHISM USEFUL FOR ASSISTANCE/THERAPY FOR SMOKING CESSATION
- 专利标题(中): 基因多态性有助于帮助/治疗吸烟
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申请号: US12310114申请日: 2007-08-09
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公开(公告)号: US20100003681A1公开(公告)日: 2010-01-07
- 发明人: Junichi Azuma , Yasushi Fujio , Chieko Taniguchi , Tsuyoshi Fukuda , Makiko Maeda , Tomoko Kubota , Etsuko Tange , Risa Ueki
- 申请人: Junichi Azuma , Yasushi Fujio , Chieko Taniguchi , Tsuyoshi Fukuda , Makiko Maeda , Tomoko Kubota , Etsuko Tange , Risa Ueki
- 优先权: JP2006-219930 20060811
- 国际申请: PCT/JP2007/065605 WO 20070809
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
Disclosed is a method for determination of a smoking trend in a subject which is useful for the assistance or therapy for smoking cessation, which comprises the steps of detecting one or more polymorphisms occurring on one or more genes selected from the genes (1) to (3) or a genome or in the neighborhood of the genes or the genome and determining the smoking trend based on the results of the detection: (1) nicotinic acetylcholine receptor β2 subunit (CHRNB2) gene; (2) serotonin transporter (SLC6A4(5HTT)) gene; and (3) nicotinic acetylcholine receptor α4 subunit (CHRNA4) gene.
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