发明申请
- 专利标题: METHOD OF PROGNOSIS
- 专利标题(中): 预防方法
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申请号: US12439322申请日: 2007-08-28
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公开(公告)号: US20100004140A1公开(公告)日: 2010-01-07
- 发明人: Mark William James Ferguson , Hugh Gerald Laverty , Nicholas Occleston , Sharon O'Kane , Darren Hodgson , Neil French , Claire Cridland , Philip Roby , Ardeshir Bayat
- 申请人: Mark William James Ferguson , Hugh Gerald Laverty , Nicholas Occleston , Sharon O'Kane , Darren Hodgson , Neil French , Claire Cridland , Philip Roby , Ardeshir Bayat
- 申请人地址: GB Manchester
- 专利权人: Renovo Limited
- 当前专利权人: Renovo Limited
- 当前专利权人地址: GB Manchester
- 优先权: GB0617120.1 20060831
- 国际申请: PCT/GB2007/003241 WO 20070828
- 主分类号: C40B40/06
- IPC分类号: C40B40/06 ; C12Q1/68 ; C40B40/10
摘要:
Provided are methods, kits and arrays for use in determining susceptibility to keloid formation. These determine susceptibility based on comparison of gene expression in a patient of interest with expression in a control sample. If expression of at least one gene, selected from the group of genes set out in Table 1, is increased in a sample representative of gene expression in the patient compared to expression of the same gene (or genes) in the control sample this is indicative of a susceptibility to keloid formation.