发明申请
- 专利标题： P-38 INHIBITORS
- 专利标题（中）： P-38抑制剂
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申请号： US12557835申请日： 2009-09-11
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公开(公告)号： US20100004298A1公开(公告)日： 2010-01-07
- 发明人: Qing Dong , Fabrice Pierre , Jianqiang Wang
- 申请人： Qing Dong , Fabrice Pierre , Jianqiang Wang
- 主分类号： A61K31/426
- IPC分类号： A61K31/426 ; C07D277/18 ; C12N9/99 ; A61P29/00 ; A61P37/00 ; A61P25/00 ; A61P31/12 ; A61P19/08 ; C07D285/08 ; C07D285/12 ; C07D271/06 ; C07D249/14 ; C07D263/02 ; A61K31/433 ; A61K31/4245 ; A61K31/421 ; A61K31/4196
摘要：
Provided are 5-membered heterocycle-based p38 kinase, including p38α and p38β kinase, inhibitors. Pharmaceutical compositions containing the compounds are also provided. Methods of use of the compounds and compositions are also provided, including methods of treatment, prevention, or amelioration of one or more symptoms of p38 kinase mediated diseases and disorders, including, but not limited to, inflammatory diseases and disorders.