Invention Application
- Patent Title: SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE
- Patent Title (中): 螺环杂环衍生物及其使用方法
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Application No.: US12542302Application Date: 2009-08-17
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Publication No.: US20100029614A1Publication Date: 2010-02-04
- Inventor: Roland E. Dolle , Bertrand Le Bourdonnec , Guo-Hua Chu
- Applicant: Roland E. Dolle , Bertrand Le Bourdonnec , Guo-Hua Chu
- Applicant Address: US PA Exton
- Assignee: Adolor Corporation
- Current Assignee: Adolor Corporation
- Current Assignee Address: US PA Exton
- Main IPC: A61K31/438
- IPC: A61K31/438 ; C07D491/107 ; C07D307/94 ; A61K31/496 ; A61K31/5377 ; A61K31/55 ; A61K31/352
Abstract:
Spirocyclic heterocyclic derivatives, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of the δ opioid receptor and may be useful, inter alia, for treating and/or preventing pain, anxiety, gastrointestinal disorders, and other δ opioid receptor-mediated conditions.
Public/Granted literature
- US08022060B2 Spirocyclic heterocyclic derivatives and methods of their use Public/Granted day:2011-09-20
Information query
