发明申请
- 专利标题： MONOARYL AMINOTETRALINES
- 专利标题（中）： 单价AMINOTETRALINES
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申请号： US12540780申请日： 2009-08-13
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公开(公告)号： US20100041760A1公开(公告)日： 2010-02-18
- 发明人: Jean-Baptiste Blanc , Li Chen , Fariborz Firooznia , Paul Gillespie , Robert Alan Goodnow, JR. , Tai-An Lin , Song Pan , Sung-Sau So , HongYing Yun
- 申请人： Jean-Baptiste Blanc , Li Chen , Fariborz Firooznia , Paul Gillespie , Robert Alan Goodnow, JR. , Tai-An Lin , Song Pan , Sung-Sau So , HongYing Yun
- 主分类号： A61K31/18
- IPC分类号： A61K31/18 ; C07C311/00
摘要：
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein R1, R2 and R3 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
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