发明申请
- 专利标题： QUINAZOLINES FOR PDK1 INHIBITION
- 专利标题（中）： 用于PDK1抑制剂的喹唑啉
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申请号： US12295967申请日： 2007-04-05
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公开(公告)号： US20100048561A1公开(公告)日： 2010-02-25
- 发明人: Savithri Ramurthy , Xiaodong Lin , Sharadha Subramanian , Alice C. Rico , Xiaojing M. Wang , Rama Jain , Jeremy M. Murray , Steven E. Basham , Robert L. Warne , Wei Shu , Yasheen Zhou , Jeffrey Dove , Mina Aikawa , Payman Amiri , Weibo Wang , Johanna M. Jansen , Allan S. Wagman , Keith B. Pfister , Simon Ng
- 申请人： Savithri Ramurthy , Xiaodong Lin , Sharadha Subramanian , Alice C. Rico , Xiaojing M. Wang , Rama Jain , Jeremy M. Murray , Steven E. Basham , Robert L. Warne , Wei Shu , Yasheen Zhou , Jeffrey Dove , Mina Aikawa , Payman Amiri , Weibo Wang , Johanna M. Jansen , Allan S. Wagman , Keith B. Pfister , Simon Ng
- 申请人地址： US CA Emmeryville
- 专利权人： NOVARTIS VACCINES & DIAGNOSTICS, INC.
- 当前专利权人： NOVARTIS VACCINES & DIAGNOSTICS, INC.
- 当前专利权人地址： US CA Emmeryville
- 优先权： US60/790304 20060406
- 国际申请： PCT/US2007/008592 WO 20070405
- 主分类号： A61K31/517
- IPC分类号： A61K31/517 ; C07D401/12 ; C07D401/14 ; C07D239/84 ; C07D413/14 ; A61K31/5377 ; A61P35/00
摘要：
The invention provides quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.
公开/授权文献
- US07932262B2 Quinazolines for PDK1 inhibition 公开/授权日：2011-04-26
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