发明申请
- 专利标题： THIAZOLIDINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF
- 专利标题（中）： 噻唑烷衍生物及其制备方法
-
申请号： US12523285申请日： 2008-01-16
-
公开(公告)号： US20100048570A1公开(公告)日： 2010-02-25
- 发明人: Sung Soo Kim , Jin Hee Ahn , Hyae Gyeong Cheon , Sang Dal Rhee , Nam Sook Kang , Ki Young Kim , Seung Kyu Kang , Won Hoon Jung , Sung Gyu Kim , Sun Young Kim , Jae Hong Kweon , Sang Kwon Sohn , Min Ki Shin , Ni Na Ha
- 申请人： Sung Soo Kim , Jin Hee Ahn , Hyae Gyeong Cheon , Sang Dal Rhee , Nam Sook Kang , Ki Young Kim , Seung Kyu Kang , Won Hoon Jung , Sung Gyu Kim , Sun Young Kim , Jae Hong Kweon , Sang Kwon Sohn , Min Ki Shin , Ni Na Ha
- 申请人地址： KR Gangnam-gu, Seoul KR Daejeon KR Gangdong-gu, Seoul
- 专利权人： Kainos Medicine, Inc,Korea Research Institute of Chemical Technology,Yungjin Pharmaceutical Company, Ltd
- 当前专利权人： Kainos Medicine, Inc,Korea Research Institute of Chemical Technology,Yungjin Pharmaceutical Company, Ltd
- 当前专利权人地址： KR Gangnam-gu, Seoul KR Daejeon KR Gangdong-gu, Seoul
- 优先权： KR10-2007-0004577 20070116
- 国际申请： PCT/IB08/00773 WO 20080116
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D277/00 ; C07D415/00 ; A61K31/426
摘要：
The present invention relates to novel 2-carbonyl-3-acyl-1,3-thiazolidines having a β-amino group on the acyl chain, in free, prodrug form or pharmaceutically acceptable salt thereof, including their enantiomers, diastereomers and racemates, as efficient inhibitors against DPP-IV. The invention further relates to the pharmaceutical compositions comprising the disclosed compounds. The present invention also relates to methods for preparing the disclosed compounds and for treating DPP-IV-mediated diseases.
信息查询
IPC分类:
