Invention Application
- Patent Title: PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS
- Patent Title (中): 吡啶衍生物及其作为治疗剂的用途
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Application No.: US12552868Application Date: 2009-09-02
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Publication No.: US20100048584A1Publication Date: 2010-02-25
- Inventor: Melwyn Abreo , Daniel F. Harvey , Heinz W. Gschwend , Wenbao Li , Chi Tu , Rajender Kamboj , Michael D. Winther , Vishnumurthy Kodumuru , Cindy J. Hudson , Mikhail A. Kondratenko , Shifeng Liu , Vandna Raina , Serguei Sviridov , Zaihui Zhang , Mehran Seid Bagherzadeh , Shaoyi Sun
- Applicant: Melwyn Abreo , Daniel F. Harvey , Heinz W. Gschwend , Wenbao Li , Chi Tu , Rajender Kamboj , Michael D. Winther , Vishnumurthy Kodumuru , Cindy J. Hudson , Mikhail A. Kondratenko , Shifeng Liu , Vandna Raina , Serguei Sviridov , Zaihui Zhang , Mehran Seid Bagherzadeh , Shaoyi Sun
- Applicant Address: CA Burnaby
- Assignee: XENON PHARMACEUTICALS INC.
- Current Assignee: XENON PHARMACEUTICALS INC.
- Current Assignee Address: CA Burnaby
- Main IPC: A61K31/496
- IPC: A61K31/496 ; C12N9/99 ; A61P3/04 ; A61P3/00 ; C07D401/04 ; C07D401/14
Abstract:
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): wherein x, y, W, V, R1, R2, R3, R4, R5, R6, R7, R7a, R8, R8a, R9, R9a, R10 and R10a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Public/Granted literature
- US08153636B2 Pyridyl derivatives and their use as therapeutic agents Public/Granted day:2012-04-10
Information query
IPC分类:
