发明申请
- 专利标题： PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS
- 专利标题（中）： 吡啶衍生物及其作为治疗剂的用途
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申请号： US12552868申请日： 2009-09-02
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公开(公告)号： US20100048584A1公开(公告)日： 2010-02-25
- 发明人: Melwyn Abreo , Daniel F. Harvey , Heinz W. Gschwend , Wenbao Li , Chi Tu , Rajender Kamboj , Michael D. Winther , Vishnumurthy Kodumuru , Cindy J. Hudson , Mikhail A. Kondratenko , Shifeng Liu , Vandna Raina , Serguei Sviridov , Zaihui Zhang , Mehran Seid Bagherzadeh , Shaoyi Sun
- 申请人： Melwyn Abreo , Daniel F. Harvey , Heinz W. Gschwend , Wenbao Li , Chi Tu , Rajender Kamboj , Michael D. Winther , Vishnumurthy Kodumuru , Cindy J. Hudson , Mikhail A. Kondratenko , Shifeng Liu , Vandna Raina , Serguei Sviridov , Zaihui Zhang , Mehran Seid Bagherzadeh , Shaoyi Sun
- 申请人地址： CA Burnaby
- 专利权人： XENON PHARMACEUTICALS INC.
- 当前专利权人： XENON PHARMACEUTICALS INC.
- 当前专利权人地址： CA Burnaby
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C12N9/99 ; A61P3/04 ; A61P3/00 ; C07D401/04 ; C07D401/14
摘要：
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): wherein x, y, W, V, R1, R2, R3, R4, R5, R6, R7, R7a, R8, R8a, R9, R9a, R10 and R10a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
公开/授权文献
- US08153636B2 Pyridyl derivatives and their use as therapeutic agents 公开/授权日：2012-04-10
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