发明申请
- 专利标题: COMPUTER-IMPLEMENTED BIOLOGICAL SEQUENCE IDENTIFIER SYSTEM AND METHOD
- 专利标题(中): 计算机实现生物学序列识别系统和方法
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申请号: US12617025申请日: 2009-11-12
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公开(公告)号: US20100070195A1公开(公告)日: 2010-03-18
- 发明人: Anthony P. Malanoski , Baochuan Lin , Joel M. Schnur , David A. Stenger
- 申请人: Anthony P. Malanoski , Baochuan Lin , Joel M. Schnur , David A. Stenger
- 申请人地址: US DC Washington
- 专利权人: The Government of the United States of America, as represented by the Secretary of the Navy
- 当前专利权人: The Government of the United States of America, as represented by the Secretary of the Navy
- 当前专利权人地址: US DC Washington
- 主分类号: G06F19/00
- IPC分类号: G06F19/00
摘要:
A method of: submitting reference sequences to a taxonomic database to produce taxonomic results; and reporting a taxonomic identification based on the taxonomic results. The reference sequences are the output of genetic database queries that return a score for each reference sequence. A method for processing a biological sequence obtained from an assay by: converting base calls located in a predetermined list of positions within the biological sequence to N; and determining the ratio of single nucleotide polymorphisms in the biological sequence relative to a reference sequence. Each entry in the predetermined list of positions represents the capability of a substance hybridizing to a microarray used to generate the biological sequence. The substance is not the nucleic acid of a target pathogen.
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