发明申请
US20100075953A1 SUBSTITUTED PIPERAZINES, (1,4) DIAZEPINES, AND 2,5-DIAZABICYCLO (2.2.1) HEPTANES AS HISTAMINE H1 AND/OR H3 ANTAGONISTS OR HISTAMINE H3 REVERSE ANTAGONISTS
审中-公开
替代哌嗪，（1,4）双嘧达嗪和2,5-DIAZABICYCLO（2.2.1）作为组胺H1和/或H3拮抗剂或组胺H3逆转拮抗剂的HEPTANES
- 专利标题： SUBSTITUTED PIPERAZINES, (1,4) DIAZEPINES, AND 2,5-DIAZABICYCLO (2.2.1) HEPTANES AS HISTAMINE H1 AND/OR H3 ANTAGONISTS OR HISTAMINE H3 REVERSE ANTAGONISTS
- 专利标题（中）： 替代哌嗪，（1,4）双嘧达嗪和2,5-DIAZABICYCLO（2.2.1）作为组胺H1和/或H3拮抗剂或组胺H3逆转拮抗剂的HEPTANES
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申请号： US12562285申请日： 2009-09-18
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公开(公告)号： US20100075953A1公开(公告)日： 2010-03-25
- 发明人: Rachael Ancliff , Colin David Eldred , Ashley Paul Hancock , Thomas Daniel Heightman , Heather Hobbs , Simon Teanby Hodgson , David Matthew Wilson
- 申请人： Rachael Ancliff , Colin David Eldred , Ashley Paul Hancock , Thomas Daniel Heightman , Heather Hobbs , Simon Teanby Hodgson , David Matthew Wilson
- 申请人地址： GB Greenford
- 专利权人： Glaxo Group Limited
- 当前专利权人： Glaxo Group Limited
- 当前专利权人地址： GB Greenford
- 优先权： GB0224084.4 20021016
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61K31/55 ; A61K31/551 ; A61K31/541 ; A61K31/538 ; C07D403/12 ; C07D405/14 ; C07D417/12 ; C07D401/12 ; C07D401/14 ; A61P11/00
摘要：
The present invention relates to novel piperazine and azepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurodegenerative disorders including Alzheimer's disease.
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