发明申请
US20100075998A1 TRICYCLIC INDOLES AND (4,5-DIHYDRO) INDOLES 有权
三聚吲哚和(4,5-二羟基)吲哚

TRICYCLIC INDOLES AND (4,5-DIHYDRO) INDOLES
摘要:
The present invention provides tricyclic indoles and (4,5-dihydro) indoles of the formula (I) or a pharmaceutically acceptable salt thereof: wherein the ring A represents a fused pyrazole, pyridine or pyrimidine, means either simple or double carbon-carbon bond and R1, R2 and R3 are as defined in the specification. Further objects of the invention are a process for the preparation of the compounds of the formula (I), pharmaceutical compositions comprising them and methods for treating cell proliferative disorders. As a matter of fact, the compounds of the formula (I) are useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, in particular Cdc7 and AKT kinase activity, like cancer.
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