发明申请
- 专利标题: Atopic dermatitis inducer
- 专利标题(中): 特应性皮炎诱导剂
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申请号: US12461368申请日: 2009-08-10
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公开(公告)号: US20100080854A1公开(公告)日: 2010-04-01
- 发明人: Michihiro Hide , Toshihiko Tanaka , Akio Tanaka , Kaori Ishii , Hidenori Suzuki
- 申请人: Michihiro Hide , Toshihiko Tanaka , Akio Tanaka , Kaori Ishii , Hidenori Suzuki
- 优先权: JP2003-194642 20030709
- 主分类号: A61K35/55
- IPC分类号: A61K35/55 ; A61P17/00
摘要:
An atopic dermatitis inducer binding to a human own IgE antibody and activating mast cells and basophiles, which includes a purified human secretion fraction, or an antigenic molecule or an antigenic determinant in the purified fraction, and obtained through the following steps of: filtering a human secretion, removing insoluble matters and collecting the filtrate; mixing the filtrate with a ConA-affinity carrier and collecting the supernatant; and separating a component having a histamine-releasing activity from the supernatant by column chromatography. This inducer is effective in diagnosing and treating human atopic dermatitis.
公开/授权文献
- US08129507B2 Atopic dermatitis inducer 公开/授权日:2012-03-06