发明申请
US20100093770A1 THERAPEUTIC AGENT FOR GLAUCOMA CONTAINING ADENOSINE DERIVATIVE AS ACTIVE INGREDIENT
审中-公开
含有腺苷衍生物的GLAUCOMA治疗药物作为主动成分
- 专利标题: THERAPEUTIC AGENT FOR GLAUCOMA CONTAINING ADENOSINE DERIVATIVE AS ACTIVE INGREDIENT
- 专利标题(中): 含有腺苷衍生物的GLAUCOMA治疗药物作为主动成分
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申请号: US12450832申请日: 2008-04-14
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公开(公告)号: US20100093770A1公开(公告)日: 2010-04-15
- 发明人: Atsushi Shimazaki , Noriko Kawabata , Tomoko Kirihara , Jayson M. Rieger , Robert D. Thompson
- 申请人: Atsushi Shimazaki , Noriko Kawabata , Tomoko Kirihara , Jayson M. Rieger , Robert D. Thompson
- 优先权: JP2007-106915 20070416
- 国际申请: PCT/US08/04770 WO 20080414
- 主分类号: A61K31/52
- IPC分类号: A61K31/52 ; A61P27/06
摘要:
A method for treating glaucoma or ocular hypertension comprising administering to a patient a pharmacologically effective amount of a compound represented by the following (1) or a salt thereof: wherein X represents CH or N; R1 represents a hydrogen atom, a hydroxy group, a halogen atom, an alkyl group, an alkoxy group, a cycloalkyl group, a cycloalkoxy group, a (cycloalkyl)methoxy group, or R2 represents a hydrogen atom, an alkyl group, a cycloalkyl group, an alkylcarbonyl group or an alkyloxycarbonyl group; and Ra and Rb are the same or different and represent a hydrogen atom, a hydroxy group, a halogen atom, an alkyl group, an alkoxy group, a cycloalkyl group or a cycloalkoxy group.
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