发明申请
US20100099644A1 HPMA - DOCETAXEL OR GEMCITABINE CONJUGATES AND USES THEREFORE
有权
HPMA - DOCETAXEL或GEMCITABINE CONJUGATES及其用途
- 专利标题: HPMA - DOCETAXEL OR GEMCITABINE CONJUGATES AND USES THEREFORE
- 专利标题(中): HPMA - DOCETAXEL或GEMCITABINE CONJUGATES及其用途
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申请号: US12575276申请日: 2009-10-07
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公开(公告)号: US20100099644A1公开(公告)日: 2010-04-22
- 发明人: Young B. Lee , Deog J. Kim , Chang H. Ahn , Anjan Nan , Hamidreza Ghandehari , Abhijit Ray
- 申请人: Young B. Lee , Deog J. Kim , Chang H. Ahn , Anjan Nan , Hamidreza Ghandehari , Abhijit Ray
- 主分类号: A61K47/48
- IPC分类号: A61K47/48
摘要:
Disclosed are water-soluble compositions of gemcitabine and docetaxel formed by conjugating the gemcitabine or docetaxel to a water-soluble polymer such as N-2-hydroxypropyl methacrylamide (HPMA). Also disclosed are methods of using the compositions of the invention for the treatment of cancer.
公开/授权文献
- US09434610B2 HPMA—docetaxel conjugates and uses therefore 公开/授权日:2016-09-06
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