发明申请
- 专利标题： AN INSULINOTROPIC COMPLEX USING AN IMMUNOGLOBULIN FRAGMENT
- 专利标题（中）： 使用免疫抑制蛋白片段的胰岛素复合物
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申请号： US12523050申请日： 2008-01-04
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公开(公告)号： US20100105877A1公开(公告)日： 2010-04-29
- 发明人: Dae Hae Song , Chang Ki Lim , Tae Hun Song , Young Hoon Kim , Se Chang Kwon , Gwan Sun Lee , Sung Youb Jung , In Young Choi
- 申请人： Dae Hae Song , Chang Ki Lim , Tae Hun Song , Young Hoon Kim , Se Chang Kwon , Gwan Sun Lee , Sung Youb Jung , In Young Choi
- 申请人地址： KR Gyeonggi-do
- 专利权人： HANMI PHARMACEUTICAL CO., LTD.
- 当前专利权人： HANMI PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： KR Gyeonggi-do
- 优先权： KR10-2007-0001662 20070105
- 国际申请： PCT/KR08/00061 WO 20080104
- 主分类号： C07K16/00
- IPC分类号： C07K16/00
摘要：
The present invention relates to an insulinotropic peptide conjugate having improved in-vivo duration of efficacy and stability, comprising an insulinotropic peptide, a non-peptide polymer and an immunoglobulin Fc region, which are covalently linked to each other, and a use of the same. The insulinotropic peptide conjugate of the present invention has the in-vivo activity which is maintained relatively high, and has remarkably increased blood half-life, and thus it can be desirably employed in the development of long acting formulations of various peptide drugs.
公开/授权文献
- US08476230B2 Insulinotropic complex using an immunoglobulin fragment 公开/授权日：2013-07-02
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