发明申请
US20100113465A1 7-AZASPIRO[3.5]NONANE-7-CARBOXAMIDE COMPOUNDS
审中-公开
7-AZASPIRO [3.5] NONANE-7-羧酰胺化合物
- 专利标题: 7-AZASPIRO[3.5]NONANE-7-CARBOXAMIDE COMPOUNDS
- 专利标题(中): 7-AZASPIRO [3.5] NONANE-7-羧酰胺化合物
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申请号: US12573897申请日: 2009-10-06
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公开(公告)号: US20100113465A1公开(公告)日: 2010-05-06
- 发明人: Scott A. Long , Marvin J. Meyers , Matthew J. Pelc , Barbara A. Schweitzer , Atli Thorarensen , Jane L. Wang
- 申请人: Scott A. Long , Marvin J. Meyers , Matthew J. Pelc , Barbara A. Schweitzer , Atli Thorarensen , Jane L. Wang
- 专利权人: Pfizer Inc.
- 当前专利权人: Pfizer Inc.
- 主分类号: A61K31/501
- IPC分类号: A61K31/501 ; C07D221/20 ; A61K31/438 ; A61P29/00 ; C07D401/14
摘要:
Provided herein are 7-azaspiro[3.5]nonane-7-carboxamide compounds and the pharmaceutically acceptable salts of such compounds useful in treating diseases or conditions associated with fatty acid amide hydrolase (FAAH) activity, conditions including including acute pain, chronic pain, neuropathic pain, nociceptive pain, inflammatory pain, cancer and cancer pain, fibromyalgia, rheumatoid arthritis, inflammatory bowel disease, lupus, diabetes, allergic asthma, vascular inflammation, urinary incontinence, overactive bladder, emesis, cognitive disorders, anxiety, depression, sleeping disorders, eating disorders, movement disorders, glaucoma, psoriasis, multiple sclerosis, cerebrovascular disorders, brain injury, gastrointestinal disorders, hypertension, or cardiovascular disease.
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