发明申请
US20100113528A1 OXADIAZOLE SUBSTITUTED INDAZOLE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE (S1P) AGONISTS
失效
用作磷酸1-磷酸(S1P)激动剂的奥氮唑取代的吲哚衍生物
- 专利标题: OXADIAZOLE SUBSTITUTED INDAZOLE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE (S1P) AGONISTS
- 专利标题(中): 用作磷酸1-磷酸(S1P)激动剂的奥氮唑取代的吲哚衍生物
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申请号: US12596488申请日: 2008-04-17
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公开(公告)号: US20100113528A1公开(公告)日: 2010-05-06
- 发明人: Mahmood Ahmed , Gerard Martin Paul Giblin , James Myatt , David Norton , Dean Andrew Rivers
- 申请人: Mahmood Ahmed , Gerard Martin Paul Giblin , James Myatt , David Norton , Dean Andrew Rivers
- 专利权人: Glaxo Group Limited
- 当前专利权人: Glaxo Group Limited
- 优先权: GB0707617.7 20070419; GB0805993.3 20080402
- 国际申请: PCT/EP08/54647 WO 20080417
- 主分类号: A61K31/4439
- IPC分类号: A61K31/4439 ; C07D271/06 ; C07D413/04 ; A61K31/4245 ; A61P37/06 ; A61P35/00 ; A61P1/06
摘要:
The present invention provides compounds of formula (I) or salts thereof: having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders mediated by S1P1 receptors.
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