发明申请
- 专利标题： METHODS FOR INDUCING POLYPLOIDIZATION OF MEGAKARYOCYTES AND FOR TREATING BLOOD AND BONE MARROW DISEASES AND DISORDERS
- 专利标题（中）： 诱导多糖的多分支化合物和治疗血液和骨髓疾病和疾病的方法
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申请号： US12613996申请日： 2009-11-06
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公开(公告)号： US20100120750A1公开(公告)日： 2010-05-13
- 发明人: John D. Crispino , Qiang Wen , Zan Huang , Andrew M. Stern , Robert J. Gould
- 申请人： John D. Crispino , Qiang Wen , Zan Huang , Andrew M. Stern , Robert J. Gould
- 申请人地址： US IL Evanston
- 专利权人： Northwestern University
- 当前专利权人： Northwestern University
- 当前专利权人地址： US IL Evanston
- 主分类号： A61K31/5513
- IPC分类号： A61K31/5513 ; C12N5/071 ; C12N5/02 ; A61K31/4439 ; A61P7/00
摘要：
Disclosed are methods for inducing polyploidization of megakaryocyte cells and for promoting differentiation of megakaryocyte cells into platelet-producing cells. The methods may be utilized for treating blood and bone marrow diseases and disorders in a subject in need thereof and for identifying agents for treating blood and bone marrow diseases and disorders.
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