发明申请
US20100124547A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF FACTOR VII GENES
审中-公开
抑制因子VII基因表达的组合物和方法
- 专利标题： COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF FACTOR VII GENES
- 专利标题（中）： 抑制因子VII基因表达的组合物和方法
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申请号： US12616828申请日： 2009-11-12
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公开(公告)号： US20100124547A1公开(公告)日： 2010-05-20
- 发明人: Birgit Bramlage , Rainer Constien , Jacques Himber , Markus Hossbach , Pamela Tan , Hans-Peter Vornlocher
- 申请人： Birgit Bramlage , Rainer Constien , Jacques Himber , Markus Hossbach , Pamela Tan , Hans-Peter Vornlocher
- 优先权： EP08169301.2 20081117
- 主分类号： A61K35/12
- IPC分类号： A61K35/12 ; C12N5/10 ; C12N5/02 ; C12N15/63 ; A61K31/7088 ; C07H21/02 ; A01K67/00
摘要：
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a Factor VII gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of a Factor VII gene using said pharmaceutical composition; and methods for inhibiting the expression of Factor VII in a cell.