发明申请
- 专利标题： Bead-Based Multiplexed Analytical Methods and Instrumentation
- 专利标题（中）： 基于珠的多重分析方法和仪器
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申请号： US12596897申请日： 2008-03-24
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公开(公告)号： US20100130369A1公开(公告)日： 2010-05-27
- 发明人: Alexander Shenderov , Richard Kouri , Varvara Grichko
- 申请人： Alexander Shenderov , Richard Kouri , Varvara Grichko
- 申请人地址： US NC Research Triangle Park
- 专利权人： ADVANCED LIQUID LOGIC, INC.
- 当前专利权人： ADVANCED LIQUID LOGIC, INC.
- 当前专利权人地址： US NC Research Triangle Park
- 国际申请： PCT/US08/58018 WO 20080324
- 主分类号： C40B30/00
- IPC分类号： C40B30/00 ; C40B50/08
摘要：
Various methods, such as a method of detecting SNPs, involving (a) introducing onto a droplet actuator a solution comprising genomic DNA, extension oligos and suspension array beads; (b) dispensing on the droplet actuator one bead per droplet; (c) cleaving DNA from the bead in each droplet; (d) amplifying the cleaved DNA; (e) detecting SNP signals and barcode signals from the amplified DNA.