发明申请
US20100130600A1 LIPOPROTEIN LIPASE AND ITS EFFECT ON STATIN TREATMENTS
审中-公开
LIPOPROTEIN脂肪酶及其对肌肉抑制素的影响
- 专利标题： LIPOPROTEIN LIPASE AND ITS EFFECT ON STATIN TREATMENTS
- 专利标题（中）： LIPOPROTEIN脂肪酶及其对肌肉抑制素的影响
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申请号： US12594143申请日： 2008-03-28
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公开(公告)号： US20100130600A1公开(公告)日： 2010-05-27
- 发明人: Mark O. Goodarzi , Kent D. Taylor , Maren T. Scheuner , Xiuqing Guo , Prediman K. Shah , Jerome I. Rotter
- 申请人： Mark O. Goodarzi , Kent D. Taylor , Maren T. Scheuner , Xiuqing Guo , Prediman K. Shah , Jerome I. Rotter
- 申请人地址： US CA Los Angeles
- 专利权人： CEDARS-SINAI MEDICAL CENTER
- 当前专利权人： CEDARS-SINAI MEDICAL CENTER
- 当前专利权人地址： US CA Los Angeles
- 国际申请： PCT/US08/58623 WO 20080328
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; A61K31/366
摘要：
The invention provides methods of treating and prognosing atherosclerosis and lipid response to statin treatment by determining the presence or absence of haplotypes at the lipoprotein lipase locus. In one embodiment, the invention is practiced by evaluating the prognosis of vascular grafts in an individual undergoing statin treatment by determining the presence or absence of haplotypes at the lipoprotein locus.
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