发明申请
- 专利标题: RHO-KINASE INHIBITORS
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申请号: US12698386申请日: 2010-02-02
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公开(公告)号: US20100137324A1公开(公告)日: 2010-06-03
- 发明人: Dhanaphalan Nagarathnam , Davoud Asgari , Jianxing Shao , Xiao-Gao Liu , Uday Khire , Chunguang Wang , Barry Hart , Stephen Boyer , Olaf Weber , Mark Lynch
- 申请人: Dhanaphalan Nagarathnam , Davoud Asgari , Jianxing Shao , Xiao-Gao Liu , Uday Khire , Chunguang Wang , Barry Hart , Stephen Boyer , Olaf Weber , Mark Lynch
- 主分类号: A61K31/517
- IPC分类号: A61K31/517 ; C07D403/12 ; C07D405/14 ; C07D409/14 ; C07D413/14 ; C07D403/14 ; A61P9/10 ; A61P25/00 ; A61P35/00
摘要:
Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
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