发明申请
US20100137603A1 DIALKYLPHENYL COMPOUNDS HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY
失效
具有BETA2 ADRENERGIC受体激动剂和MUSCARINIC受体拮抗剂活性的二烷基苯酚化合物
- 专利标题: DIALKYLPHENYL COMPOUNDS HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY
- 专利标题(中): 具有BETA2 ADRENERGIC受体激动剂和MUSCARINIC受体拮抗剂活性的二烷基苯酚化合物
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申请号: US12701108申请日: 2010-02-05
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公开(公告)号: US20100137603A1公开(公告)日: 2010-06-03
- 发明人: Pierre-Jean Colson , Adam D. Hughes , Craig Husfeld , Mathai Mammen , Miroslav Rapta
- 申请人: Pierre-Jean Colson , Adam D. Hughes , Craig Husfeld , Mathai Mammen , Miroslav Rapta
- 申请人地址: US CA South San Francisco
- 专利权人: THERAVANCE, INC.
- 当前专利权人: THERAVANCE, INC.
- 当前专利权人地址: US CA South San Francisco
- 主分类号: C07D405/12
- IPC分类号: C07D405/12 ; C07D211/44
摘要:
This invention relates to compounds of formula I: wherein R1 and R2 are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The invention also relates to pharmaceutical compositions and combinations comprising such compounds, processes and intermediates for preparing such compounds, and methods of using such compound to, for example, treat pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.
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