发明申请
- 专利标题: USES OF MONOCLONAL ANTIBODY 8H9
- 专利标题(中): 单克隆抗体8H9的用途
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申请号: US12531828申请日: 2008-03-24
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公开(公告)号: US20100143245A1公开(公告)日: 2010-06-10
- 发明人: Nai-Kong V. Cheung
- 申请人: Nai-Kong V. Cheung
- 申请人地址: US NY New York
- 专利权人: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
- 当前专利权人: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
- 当前专利权人地址: US NY New York
- 国际申请: PCT/US08/58030 WO 20080324
- 主分类号: A61K51/10
- IPC分类号: A61K51/10 ; A61K39/395 ; C07K16/00 ; G01N33/566 ; A61P35/00
摘要:
The present invention discloses monoclonal antibody 8H9 which binds to the 4Ig domain isoform of the human B7-homolog 3, 4Ig-B7H3. The present invention provides a method of improving the prognosis or prolonging the survival of a subject bearing tumor cells, the method comprises administering to the subject a composition comprising an effective amount of an agent capable of binding to an antigen recognized by monoclonal antibody 8H9.
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