发明申请
US20100144688A1 23-Substituted Derivatives of Lupane-type Pentacyclic Triterpenoids
审中-公开
Lupane型五环三萜类化合物的23取代衍生物
- 专利标题： 23-Substituted Derivatives of Lupane-type Pentacyclic Triterpenoids
- 专利标题（中）： Lupane型五环三萜类化合物的23取代衍生物
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申请号： US12634305申请日： 2009-12-09
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公开(公告)号： US20100144688A1公开(公告)日： 2010-06-10
- 发明人: Ali Koohang , Aye Aye Mar , Erika Szotek , Ze-Qi Xu , David A. Eiznhamer , Michael T. Flavin
- 申请人： Ali Koohang , Aye Aye Mar , Erika Szotek , Ze-Qi Xu , David A. Eiznhamer , Michael T. Flavin
- 申请人地址： US IL Woodridge
- 专利权人： ADVANCED LIFE SCIENCES, INC.
- 当前专利权人： ADVANCED LIFE SCIENCES, INC.
- 当前专利权人地址： US IL Woodridge
- 主分类号： A61K31/568
- IPC分类号： A61K31/568 ; C07J53/00 ; C07J17/00 ; C07J1/00 ; A61K31/58 ; A61P31/12 ; A61P35/00
摘要：
The present invention comprises small molecule inhibitors of cell proliferative conditions, in particular cancer and conditions associated with cancer. For example, associated malignancies include ovarian cancer, cervical cancer, breast cancer, colorectal cancer, and glioblastomas, among others. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting these diseases. Thus, the present invention also comprises pharmaceutical formulations comprising the compounds and methods of using the compounds and formulations to inhibit cancer and treat, prevent, or inhibit the foregoing diseases.
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