发明申请
- 专利标题: CRYSTAL MODIFICATIONS OF TRANSMISSION DYES
- 专利标题(中): 传染性染色体的晶体修饰
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申请号: US12597930申请日: 2008-04-28
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公开(公告)号: US20100144753A1公开(公告)日: 2010-06-10
- 发明人: Martin Vogt , Stefan Müller , Julie Grumelard , Cyrille Deshayes , Holger Paul , Jürg Haase , Thomas Ehlis
- 申请人: Martin Vogt , Stefan Müller , Julie Grumelard , Cyrille Deshayes , Holger Paul , Jürg Haase , Thomas Ehlis
- 申请人地址: US NY Tarrytown
- 专利权人: CIBA CORPORATION
- 当前专利权人: CIBA CORPORATION
- 当前专利权人地址: US NY Tarrytown
- 优先权: EP07107681.4 20070508
- 国际申请: PCT/EP08/55139 WO 20080428
- 主分类号: A61K31/4965
- IPC分类号: A61K31/4965
摘要:
Disclosed is the use of an aqueous dispersion comprising (a) a micronized sparingly soluble organic benzophenone derivative of formula (1), selected from the crystal modifications (B) and (C), wherein the crystal modification (B) is characterized by a peak in the X-ray diffraction pattern at a d-spacing of about 7.70; and wherein the crystal modification (C) is characterized by a peak in the X-ray diffraction pattern at a d-spacing of about 7.06; and (b) a dispersing agent selected from anionic, non-ionic and amphoteric surfactants; for protecting the human skin from browning and skin aging. The new crystal modification (C) represents a thermodynamically stable compound of formula (1) at 25° C. This modification is therefore suitable in dispersions comprising micro-fine particles.
公开/授权文献
- US08557820B2 Crystal modifications of transmission dyes 公开/授权日:2013-10-15
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