发明申请
US20100150827A1 PYRIDO [2, 3-D] PYRIMIDIN-7-ONE COMPOUNDS AS INHIBITORS OF P13K-ALPHA FOR THE TREATMENT OF CANCER
审中-公开
PYRIDO [2，3-D] PYRIMIDIN-7-ONE化合物作为P13K-ALPHA的抑制剂治疗癌症
![PYRIDO [2, 3-D] PYRIMIDIN-7-ONE COMPOUNDS AS INHIBITORS OF P13K-ALPHA FOR THE TREATMENT OF CANCER](/docs/US/2010-06-17/US20100150827A1/abs.jpg.600x600.jpg)
- 专利标题： PYRIDO [2, 3-D] PYRIMIDIN-7-ONE COMPOUNDS AS INHIBITORS OF P13K-ALPHA FOR THE TREATMENT OF CANCER
- 专利标题（中）： PYRIDO [2，3-D] PYRIMIDIN-7-ONE化合物作为P13K-ALPHA的抑制剂治疗癌症
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申请号： US12595226申请日： 2008-04-11
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公开(公告)号： US20100150827A1公开(公告)日： 2010-06-17
- 发明人: Chris A. Buhr , William Bajjalieh , Anagha Abhijit Joshi , Katherine Lara , Sunghoon Ma , Charles K. Marlowe , Longcheng Wang , Bryan K.S. Yeung
- 申请人： Chris A. Buhr , William Bajjalieh , Anagha Abhijit Joshi , Katherine Lara , Sunghoon Ma , Charles K. Marlowe , Longcheng Wang , Bryan K.S. Yeung
- 申请人地址： US CA South San Francisco
- 专利权人： Exelixis, Inc
- 当前专利权人： Exelixis, Inc
- 当前专利权人地址： US CA South San Francisco
- 国际申请： PCT/US08/04753 WO 20080411
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; C07D471/04 ; A61K51/00 ; A61K39/395 ; A61P35/00 ; A61P35/02
![PYRIDO [2, 3-D] PYRIMIDIN-7-ONE COMPOUNDS AS INHIBITORS OF P13K-ALPHA FOR THE TREATMENT OF CANCER](/abs-image/US/2010/06/17/US20100150827A1/abs.jpg.150x150.jpg)
摘要：
The invention is directed to a Compound of Formula I, II, or III. The invention provides compounds that inhibit, regulate, and/or modulate PI3K that are useful in the treatment of hyperproliferatives diseases, such as cancer.