发明申请
US20100152456A1 Intermediate compound for synthesis of viridiofungin a derivative
失效
用于合成维生素E衍生物的中间体化合物
- 专利标题： Intermediate compound for synthesis of viridiofungin a derivative
- 专利标题（中）： 用于合成维生素E衍生物的中间体化合物
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申请号： US12656579申请日： 2010-02-04
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公开(公告)号： US20100152456A1公开(公告)日： 2010-06-17
- 发明人: Tatsuya Kato , Nobuaki Kimura , Akemi Mizutani , Toshihiko Makino , Kenichi Kawasaki , Hiroshi Fukuda , Susumu Komiyama , Takuo Tsukuda
- 申请人： Tatsuya Kato , Nobuaki Kimura , Akemi Mizutani , Toshihiko Makino , Kenichi Kawasaki , Hiroshi Fukuda , Susumu Komiyama , Takuo Tsukuda
- 专利权人： CHUGAI SEIYAKU KABUSHIKI KAISHA
- 当前专利权人： CHUGAI SEIYAKU KABUSHIKI KAISHA
- 优先权： JP2005-041153 20050217
- 主分类号： C07D413/12
- IPC分类号： C07D413/12 ; C07D317/26
摘要：
A method whereby a compound having HCV replication inhibitory activity and desired optical activity can be synthesized selectively and at high yield in a small number of steps by using a compound having a specific chiral auxiliary as a starting compound is provided.A compound represented by the formula (1-8): wherein Y represents a group represented by the following formula: Q represents a protected carbonyl group; D represents —(CH2)m—R′, etc.; and n represents an integer of 0 to 10.
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