发明申请
US20100155588A1 RECOMBINANT VON WILLEBRAND FACTOR AS MOLECULAR WEIGHT MARKER FOR MASS SPECTROMETRY ANALYSES
审中-公开
重组VON WILLEBRAND因子作为分子量标记用于质谱分析
- 专利标题： RECOMBINANT VON WILLEBRAND FACTOR AS MOLECULAR WEIGHT MARKER FOR MASS SPECTROMETRY ANALYSES
- 专利标题（中）： 重组VON WILLEBRAND因子作为分子量标记用于质谱分析
-
申请号： US12639619申请日： 2009-12-16
-
公开(公告)号： US20100155588A1公开(公告)日： 2010-06-24
- 发明人: Jasmin Kemptner , Martina Marchetti-Deschmann , Roland Mueller , Andreas Ivens , Peter Turecek , Hans-Peter Schwarz , Guenter Allmaier
- 申请人： Jasmin Kemptner , Martina Marchetti-Deschmann , Roland Mueller , Andreas Ivens , Peter Turecek , Hans-Peter Schwarz , Guenter Allmaier
- 申请人地址： US IL Deerfield CH Glattpark (Opfikon) AT Wien
- 专利权人： BAXTER INTERNATIONAL INC.,BAXTER HEALTHCARE S.A.,TECHNISCHE UNIVERSITAET WIEN
- 当前专利权人： BAXTER INTERNATIONAL INC.,BAXTER HEALTHCARE S.A.,TECHNISCHE UNIVERSITAET WIEN
- 当前专利权人地址： US IL Deerfield CH Glattpark (Opfikon) AT Wien
- 主分类号： H01J49/26
- IPC分类号： H01J49/26 ; B01D59/44
摘要：
Methods for determining molecular mass of at least 150 kDa of an analyte of interest using MALDI mass spectrometry in combination with a recombinant von Willebrand factor (rVWF) molecular weight marker are disclosed. More specifically, monomeric and multimeric rVWF are used for external and internal calibration of mass spectra applied for analytes having high molecular weights above 150 kDa.