发明申请
US20100168132A1 QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR ANTAGONISTS
失效
喹啉衍生物及其作为MUSCARINIC M3受体拮抗剂的用途
- 专利标题： QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR ANTAGONISTS
- 专利标题（中）： 喹啉衍生物及其作为MUSCARINIC M3受体拮抗剂的用途
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申请号： US12721897申请日： 2010-03-11
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公开(公告)号： US20100168132A1公开(公告)日： 2010-07-01
- 发明人: Neil John Press , Stephen Paul Collingwood , Urs Baettig , Brian Cox , Sudhakar Devidasrao Garad , Hyungshul Kim , Dimitris Papoutsakis , Simon James Watson
- 申请人： Neil John Press , Stephen Paul Collingwood , Urs Baettig , Brian Cox , Sudhakar Devidasrao Garad , Hyungshul Kim , Dimitris Papoutsakis , Simon James Watson
- 优先权： GB0424284.8 20041102
- 主分类号： A61K31/439
- IPC分类号： A61K31/439 ; C07D453/00 ; C07D401/14 ; A61K31/497 ; A61K31/506 ; C07D409/14 ; A61P29/00
摘要：
Compounds of Formula (I) ; in salt or zwitterionic form wherein R1, R2, R3 and R4 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by the muscarinic M3 receptor, especially inflammatory or obstructive airways diseases. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.