发明申请
- 专利标题: ORGANOMETEALLIC COMPOUNDS
- 专利标题(中): 有机化合物
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申请号: US12449135申请日: 2008-01-25
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公开(公告)号: US20100173885A1公开(公告)日: 2010-07-08
- 发明人: Bruno Therrien , Govindasvamy Padavattan , Georg Sûss-Fink , Wee Han Ang , Paul Joseph Dyson , Lucienne Juillerat , Frédéric Schmitt
- 申请人: Bruno Therrien , Govindasvamy Padavattan , Georg Sûss-Fink , Wee Han Ang , Paul Joseph Dyson , Lucienne Juillerat , Frédéric Schmitt
- 优先权: EP07101258.7 20070126
- 国际申请: PCT/IB2008/050273 WO 20080125
- 主分类号: A61K31/555
- IPC分类号: A61K31/555 ; C07F15/00 ; A61P35/00 ; A61P29/00 ; A61P37/00
摘要:
The present invention relates to novel organometallic compounds for use as a medicine, in particular in photodynamic therapy against various diseases, such as cancer or inflammatory and/or immune disorders. The compounds comprise a central porphyrin or phtalocyanine backbone to which ligand linkers coordinated to at least one transition metal are attached. Eta-5 or eta-6 arenes further bind to the transition metal. According to a preferred embodiment, the compound is a tetranuclear Ruthenium (+II) complex.
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