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公开(公告)号：US20100173885A1
公开(公告)日：2010-07-08
申请号：US12449135
申请日：2008-01-25
申请人： Bruno Therrien , Govindasvamy Padavattan , Georg Sûss-Fink , Wee Han Ang , Paul Joseph Dyson , Lucienne Juillerat , Frédéric Schmitt
发明人： Bruno Therrien , Govindasvamy Padavattan , Georg Sûss-Fink , Wee Han Ang , Paul Joseph Dyson , Lucienne Juillerat , Frédéric Schmitt
IPC分类号： A61K31/555 , C07F15/00 , A61P35/00 , A61P29/00 , A61P37/00
CPC分类号： C07F17/02
摘要： The present invention relates to novel organometallic compounds for use as a medicine, in particular in photodynamic therapy against various diseases, such as cancer or inflammatory and/or immune disorders. The compounds comprise a central porphyrin or phtalocyanine backbone to which ligand linkers coordinated to at least one transition metal are attached. Eta-5 or eta-6 arenes further bind to the transition metal. According to a preferred embodiment, the compound is a tetranuclear Ruthenium (+II) complex.
摘要翻译： 本发明涉及用作药物的新的有机金属化合物，特别是针对各种疾病如癌症或炎性和/或免疫疾病的光动力学治疗。 化合物包含与至少一个过渡金属配位的配体连接体连接的中心卟啉或酞菁骨架。 Eta-5或eta-6芳烃进一步结合过渡金属。 根据优选的实施方案，化合物是四核钌（+ II）络合物。
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2.发明申请Expression cassette encoding a 5-enolpyruvylshikimate-3-phosphate synthase (epsps) and herbicde-tolerant plants containing it 审中-公开编码5-烯醇丙酮酸莽草酸-3-磷酸合成酶（epsps）和含有其的耐受草药植物的表达盒公开(公告)号：US20060242727A1
公开(公告)日：2006-10-26
申请号：US10538438
申请日：2003-12-10
CPC分类号： C12N15/8275
摘要： The present invention relates to a novel expression cassette comprising a nucleic acid sequence encoding an EPSPS. In particular, the present invention relates to a novel expression cassette comprising, in the direction of transcription, functionally linked to one another, a promoter regulatory sequence which is functional in plant cells or plants, a nucleic acid sequence encoding an EPSPS and a terminator sequence which is functional in plant cells or plants, characterized in that the promoter regulatory sequence is a nucleic acid sequence chosen from the promoter regulatory sequences of the CsVMV (Cassaya Vein Mosaic Virus) plant virus.
摘要翻译： 本发明涉及包含编码EPSPS的核酸序列的新型表达盒。 特别地，本发明涉及一种新的表达盒，其在转录方向上包括在功能上彼此相连的启动子调节序列，其在植物细胞或植物中是有功能的，编码EPSPS和终止子序列的核酸序列 其在植物细胞或植物中是功能性的，其特征在于启动子调节序列是选自CsVMV（Cassaya Vein Mosaic Virus）植物病毒的启动子调控序列的核酸序列。
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3.发明申请EXPRESSION CASSETTE ENCODING A 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE (EPSPS) AND HERBICIDE-TOLERANT PLANTS CONTAINING IT 有权表达CASSETTE编码一种含5-羟色胺三磷酸酯合成酶（EPSPS）和抗除草剂植物公开(公告)号：US20100105560A1
公开(公告)日：2010-04-29
申请号：US12569068
申请日：2009-09-29
CPC分类号： C12N15/8275
摘要： The present invention relates to a novel expression cassette comprising a nucleic acid sequence encoding an EPSPS. In particular, the present invention relates to a novel expression cassette comprising, in the direction of transcription, functionally linked to one another, a promoter regulatory sequence which is functional in plant cells or plants, a nucleic acid sequence encoding an EPSPS and a terminator sequence which is functional in plant cells or plants, characterized in that the promoter regulatory sequence is a nucleic acid sequence chosen from the promoter regulatory sequences of the CsVMV (Cassava Vein Mosaic Virus) plant virus.
摘要翻译： 本发明涉及包含编码EPSPS的核酸序列的新型表达盒。 特别地，本发明涉及一种新的表达盒，其在转录方向上包括在功能上彼此相连的启动子调节序列，其在植物细胞或植物中是有功能的，编码EPSPS和终止子序列的核酸序列 其在植物细胞或植物中起作用，其特征在于启动子调节序列是选自CsVMV（木薯浆静脉花叶病毒）植物病毒的启动子调控序列的核酸序列。
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4.发明授权Expression cassette encoding a 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) and herbicide-tolerant plants containing it 有权编码5-烯醇丙酮酸莽草酸-3-磷酸合成酶（EPSPS）和含有其的除草剂耐受性植物的表达盒公开(公告)号：US08536408B2
公开(公告)日：2013-09-17
申请号：US12569068
申请日：2009-09-29
IPC分类号： C12N15/82
CPC分类号： C12N15/8275
摘要： The present invention relates to a novel expression cassette comprising a nucleic acid sequence encoding an EPSPS. In particular, the present invention relates to a novel expression cassette comprising, in the direction of transcription, functionally linked to one another, a promoter regulatory sequence which is functional in plant cells or plants, a nucleic acid sequence encoding an EPSPS and a terminator sequence which is functional in plant cells or plants, characterized in that the promoter regulatory sequence is a nucleic acid sequence chosen from the promoter regulatory sequences of the CsVMV (Cassava Vein Mosaic Virus) plant virus.
摘要翻译： 本发明涉及包含编码EPSPS的核酸序列的新型表达盒。 特别地，本发明涉及一种新的表达盒，其在转录方向上包括在功能上彼此相连的启动子调节序列，其在植物细胞或植物中是有功能的，编码EPSPS和终止子序列的核酸序列 其在植物细胞或植物中起作用，其特征在于启动子调节序列是选自CsVMV（木薯浆静脉花叶病毒）植物病毒的启动子调控序列的核酸序列。
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