发明申请
- 专利标题: COMPOUND
- 专利标题(中): 复合
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申请号: US12555342申请日: 2009-09-08
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公开(公告)号: US20100173963A1公开(公告)日: 2010-07-08
- 发明人: Lok Wai Lawrence Woo , Toby Jackson , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter , Gillin Reed
- 申请人: Lok Wai Lawrence Woo , Toby Jackson , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter , Gillin Reed
- 优先权: GB0525323.2 20051213
- 主分类号: A61K31/4196
- IPC分类号: A61K31/4196 ; C07D249/08 ; C07D405/10
摘要:
There is provided a compound of Formula I wherein R3, R4, R5, R6 and R7 are independently selected from H and —Y—R8; wherein each R8 is independently selected from —OH, hydrocarbyl groups, oxyhydrocarbyl groups, cyano (—CN), nitro (—NO2), H-bond acceptors, and halogens; wherein at least one of R3, R4, R5, R6 and R7 is —Y—R8 wherein R8 is selected from substituted and unsubstituted heterocyclic rings and amino substituted phenyl groups, wherein X is a bond or a linker group; wherein Y is an optional linker group; and wherein ring A is optionally further substituted; wherein R9 is selected from H, —OH and —OSO2NR1R2; wherein R1 and R2 are independently selected from H and hydrocarbyl; wherein (a) X is a bond and at least one of R3, R4, R5, R6 and R7 is —Y—R8; OR (b) R9 is —OSO2NR1R2 or —OH and four of R3, R4, R5, R6 and R7 are H and one of R3, R4, R5, R6 and R7 is —Y—R8.
公开/授权文献
- US08093279B2 Compound 公开/授权日:2012-01-10
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