发明申请
- 专利标题: XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS
- 专利标题(中): XANTHINE衍生物作为选择性HM74A激动剂
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申请号: US12063432申请日: 2006-08-08
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公开(公告)号: US20100179128A1公开(公告)日: 2010-07-15
- 发明人: Richard Jonathan Daniel Hatley , Jag Paul Heer , John Liddle , Andrew McMurtrie Mason , Ivan Leo Pinto , Shahzad Sharooq Rahman , Ian Edward David Smith
- 申请人: Richard Jonathan Daniel Hatley , Jag Paul Heer , John Liddle , Andrew McMurtrie Mason , Ivan Leo Pinto , Shahzad Sharooq Rahman , Ian Edward David Smith
- 优先权: GB0516464.5 20050810; GB0607736.6 20060419; GB0614569.2 20060721
- 国际申请: PCT/EP06/07869 WO 20060808
- 主分类号: A61K31/55
- IPC分类号: A61K31/55 ; C07D473/04 ; A61K31/522 ; C07D519/00 ; A61K31/5377 ; A61P3/06 ; A61P3/10 ; A61P3/04 ; A61P9/04 ; A61P9/10 ; A61P7/02 ; A61P13/12
摘要:
The present invention relates to compounds of formula (I) which are xanthine derivatives, processes for the manufacture of said derivatives, pharmaceutical formulations containing these active compounds and the use of the compounds in therapy, for example, in the treatment of diseases where under-activation of the HM74A receptor contributes to the disease or where activation of the receptor will be beneficial
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