发明申请
- 专利标题： COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS
- 专利标题（中）： 化合物和组合物作为ITPKB抑制剂
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申请号： US12664651申请日： 2008-06-12
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公开(公告)号： US20100184748A1公开(公告)日： 2010-07-22
- 发明人: Badry Bursulaya , Dai Cheng , Jiqing Jiang , Donald S. Karanewsky , Yi Liu , Shifeng Pan , Yongqin Wan , Xia Wang , Yun Feng Xie , Yang Yang
- 申请人： Badry Bursulaya , Dai Cheng , Jiqing Jiang , Donald S. Karanewsky , Yi Liu , Shifeng Pan , Yongqin Wan , Xia Wang , Yun Feng Xie , Yang Yang
- 申请人地址： BM Hamilton
- 专利权人： IRM LLC
- 当前专利权人： IRM LLC
- 当前专利权人地址： BM Hamilton
- 国际申请： PCT/US08/66664 WO 20080612
- 主分类号： A61K31/536
- IPC分类号： A61K31/536 ; C07D413/14 ; A61K31/551 ; A61P35/00
摘要：
The invention provides a novel class of compounds of formula (I), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or dysregulated B cell activities, particularly diseases or disorders that involve aberrant activation of inositol 1,4,5-trisphosphate 3-kinase B (ITPKb).
公开/授权文献
- US08178526B2 Compounds and compositions as ITPKb inhibitors 公开/授权日：2012-05-15