发明申请
- 专利标题: TREATMENT OF HODGKINS LYMPHOMA
- 专利标题(中): HODGKINS LYMPHOMA的治疗
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申请号: US12593281申请日: 2008-03-28
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公开(公告)号: US20100189716A1公开(公告)日: 2010-07-29
- 发明人: Arturo Molina , Kandasamy Hariharan , Steffan Ho
- 申请人: Arturo Molina , Kandasamy Hariharan , Steffan Ho
- 申请人地址: US MA Cambridge
- 专利权人: BIOGEN IDEC INC.
- 当前专利权人: BIOGEN IDEC INC.
- 当前专利权人地址: US MA Cambridge
- 国际申请: PCT/US08/58660 WO 20080328
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C12N5/00 ; A61P35/00
摘要:
Compositions comprising CD80 antagonists and methods using these compositions are provided for the treatment of Hodgkins lymphoma. More particularly, the disclosed CD80 antagonists may be used to induce apoptosis or lysis of Hodgkins Reed-Sternberg (HRS) cells, or to inhibit HRS cell activities that promote tumor development or progression.