发明申请
US20100190811A1 PYRIMIDINE DERIVATIVES AND COMPOSITIONS AS C-KIT AND PDGFR KINASE INHIBITORS
失效
吡啶衍生物和组合物作为C-kit和PDGFR激酶抑制剂
- 专利标题： PYRIMIDINE DERIVATIVES AND COMPOSITIONS AS C-KIT AND PDGFR KINASE INHIBITORS
- 专利标题（中）： 吡啶衍生物和组合物作为C-kit和PDGFR激酶抑制剂
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申请号： US12598919申请日： 2008-05-01
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公开(公告)号： US20100190811A1公开(公告)日： 2010-07-29
- 发明人: Xiaolin Li , Xiaodong Liu , Valentina Molteni
- 申请人： Xiaolin Li , Xiaodong Liu , Valentina Molteni
- 申请人地址： BM HAMILTON
- 专利权人： IRM LLC
- 当前专利权人： IRM LLC
- 当前专利权人地址： BM HAMILTON
- 国际申请： PCT/US08/62304 WO 20080501
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D401/14 ; A61P35/00 ; A61P25/36 ; A61P25/28 ; A61P25/16 ; A61P25/00 ; A61P3/10 ; A61P3/04 ; A61P37/06 ; A61P19/02
摘要：
The invention provides a novel class of pyrimidine derivatives, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of c-kit, PDGFRα and PDGFRβ kinases.
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