发明申请
- 专利标题： Novel Substituted Piperidones as HSP Inducers
- 专利标题（中）： 新型替代哌啶酮作为HSP诱导剂
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申请号： US12452389申请日： 2008-06-24
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公开(公告)号： US20100190824A1公开(公告)日： 2010-07-29
- 发明人: Prabhat Kumar , Anookh Mohanan , Navnath Argade , Chakradhar Hadole , Appaji Mandhare , Ramesh Gupta , Shailesh Deshpande , Prashant Jamadarkhana , Poonam Joshi
- 申请人： Prabhat Kumar , Anookh Mohanan , Navnath Argade , Chakradhar Hadole , Appaji Mandhare , Ramesh Gupta , Shailesh Deshpande , Prashant Jamadarkhana , Poonam Joshi
- 优先权： IN947/KOL/2007 20070629
- 国际申请： PCT/IN2008/000400 WO 20080624
- 主分类号： A61K31/4545
- IPC分类号： A61K31/4545 ; C07D211/68 ; A61P25/28 ; A61P25/08 ; A61P9/10
摘要：
The present invention relates to novel compounds of formula (I) or (II), their pharmaceutically acceptable salts and their hydrates, solvates, stereoisomers, conformers, tautomers, polymorphs and prodrugs and also pharmaceutically acceptable compositions containing them Wherein R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification. The compounds of the present invention are HSP inducers and by virtue of this effect, useful for the treatment of various diseases accompanying pathological stress. The present invention also relates to a process for the preparation of the said novel compounds. The invention also relates to the use of the above-mentioned compounds for the preparation of medicament for use as pharmaceuticals.
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